Cause of Premenstrual Syndrome (PMS) The exact cause of PMS isn't entirely understood, but hormonal changes during the menstrual cycle, specifically fluctuations in estrogen and progesterone levels, are believed to play a significant role. These hormonal shifts can affect neurotransmitters like serotonin, which impacts mood regulation. Other factors such as stress, lifestyle habits, and underlying medical conditions can exacerbate symptoms. #best_gyecologist_in_Indore, #gynecologist_in_Indore, #gynecologist_near_me, #gynaecologist_Indore